Liver Affects on Cardiomyocytes
Faculty Mentor
Dr. Judd Case
Presentation Type
Poster
Start Date
5-8-2024 9:00 AM
End Date
5-8-2024 10:45 AM
Location
PUB NCR
Primary Discipline of Presentation
Biology
Abstract
Liver diseases have been shown to impact the heart, such as cirrhosis inducing difficulties within cardiomyocyte contractibility due to thickening of heart tissue. Heart diseases have also been shown to impact the liver as well in cases involving hepatic congestion. In this research, I will be covering the histological pathologies of cardiomyocytes in relation to the effects they may show upon liver diseases. Previous research in this field seemed to show a continuous link between the heart and liver affecting each other. This study will aim to demonstrate cardiomyocyte effects that were results of liver disease. Cardiomyocyte effects may be shown through using and analyzing histological slides of both heart and liver tissues, and will assist in addressing how the heart’s tissue physically responds to liver difficulties. Cardiac vessels, intercalated discs, fibroblasts, nucleus, and sarcomeres were documented for later comparison. So far, samples provided involving an individual with liver difficulties had demonstrated abnormalities amongst the intercalated discs, number of fibroblasts, and the myocytes appeared to be paler in dye. Other morphological areas seemed to still be normal, such as the sarcomeres. To better understand the effects of liver disease on heart tissue, next I will research how the preparation methods used to fix these slides may have affected the results, and how cardiomyocytes present postpartum to evaluate other possible explanations.
Recommended Citation
Garza, Emily Anna, "Liver Affects on Cardiomyocytes" (2024). 2024 Symposium. 10.
https://dc.ewu.edu/srcw_2024/ps_2024/p1_2024/10
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Liver Affects on Cardiomyocytes
PUB NCR
Liver diseases have been shown to impact the heart, such as cirrhosis inducing difficulties within cardiomyocyte contractibility due to thickening of heart tissue. Heart diseases have also been shown to impact the liver as well in cases involving hepatic congestion. In this research, I will be covering the histological pathologies of cardiomyocytes in relation to the effects they may show upon liver diseases. Previous research in this field seemed to show a continuous link between the heart and liver affecting each other. This study will aim to demonstrate cardiomyocyte effects that were results of liver disease. Cardiomyocyte effects may be shown through using and analyzing histological slides of both heart and liver tissues, and will assist in addressing how the heart’s tissue physically responds to liver difficulties. Cardiac vessels, intercalated discs, fibroblasts, nucleus, and sarcomeres were documented for later comparison. So far, samples provided involving an individual with liver difficulties had demonstrated abnormalities amongst the intercalated discs, number of fibroblasts, and the myocytes appeared to be paler in dye. Other morphological areas seemed to still be normal, such as the sarcomeres. To better understand the effects of liver disease on heart tissue, next I will research how the preparation methods used to fix these slides may have affected the results, and how cardiomyocytes present postpartum to evaluate other possible explanations.
